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Chromatin target of prmt1

From Wikipedia, the free encyclopedia
CHTOP
Identifiers
AliasesCHTOP, C1orf77, FL-SRAG, FOP, SRAG, SRAG-3, SRAG-5, pp7704, chromatin target of PRMT1, C10orf77
External IDsOMIM: 614206; MGI: 1913761; HomoloGene: 134556; GeneCards: CHTOP; OMA:CHTOP - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001206612
NM_001244664
NM_015607
NM_001317077

RefSeq (protein)

NP_001193541
NP_001231593
NP_001304006
NP_056422

Location (UCSC)Chr 1: 153.63 – 153.65 MbChr 3: 90.41 – 90.42 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Chromatin target of PRMT1 is a protein that in humans is encoded by the CHTOP gene.[5]

Function

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This gene encodes a small nuclear protein that is characterized by an arginine and glycine rich region. The encoded protein may be involved in cell cycle progression. This protein interacts with protein arginine methyltransferases and plays a role in the activation of estradiol-dependent transcription. Alternate splicing results in multiple transcript variants.

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000160679Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000001017Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Chromatin target of PRMT1".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.